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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T67742 | EX-A5386 | Glucocorticoid receptor modulator-1 | Glucocorticoid Receptor |
EX-A5386 (Glucocorticoid receptor modulator-1) is a potent glucocorticoid receptor modulator, IC50/EC50<100nM. | |||
T72102 | Glucocorticoid receptor modulator 1 | ||
Glucocorticoid receptor modulator 1 is a potent, orally active, non-steroidal selective glucocorticoid receptor modulator, exhibiting IC50 values of 9 nM and 130 nM against NF-κB and AP-1, respectively. It effectively re... | |||
T38983 | Dazucorilant | CORT113176 | |
Dazucorilant (CORT113176) is a non-steroidal glucocorticoid receptor (GR) modulator characterized by its high affinity and selectivity. With an impressive K i value of <1 nM in vitro, Dazucorilant proves to be an excepti... | |||
T75009 | PPARγ/GR modulator 1 | ||
PPARγ/GR Modulator 1, an orally active dual agonist for the Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Glucocorticoid Receptor (GR), exhibits Ki values of 3.3 and 33.6 μM, respectively. This compound is... | |||
T78073 | HP210 | Glucocorticoid Receptor | |
HP210, a selective glucocorticoid receptor modulator (SGRM), can suppress IL-1β and IL-6 mRNA expression, suggesting its utility in investigating inflammation-related diseases [1]. |